footnote6
The odds ratio compares the nurse-visited group to the comparison.
Model effectiveness research report last updated: 2019
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
---|---|---|---|---|---|---|---|---|---|---|
5-minute Apgar | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full, (Memphis) | 1082 children | Adjusted mean = 8.60 | Adjusted mean = 8.70 | Mean difference = -0.10 | Not available | Not statistically significant, p > 0.05 |
|
Birth weight, grams | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full (Memphis) | 1082 children | Adjusted mean = 3032.20 | Adjusted mean = 3050.40 | Mean difference = -18.20 | Not available | Not statistically significant, p > 0.05 |
|
Breastfeeding attempted, percentage | FavorableUnfavorable or ambiguousNo Effect |
2 years postnatal | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 671 children | % (adjusted) = 26.00 | Adjusted mean % = 16.00 | OR = 1.90 | HomVEE calculated = 0.37 | Statistically significant, p < 0.01 |
footnote6The odds ratio compares the nurse-visited group to the comparison. |
Gestational age, weeks | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full, (Memphis) | 1082 children | Adjusted mean = 39.00 | Adjusted mean = 39.00 | Mean difference = 0.00 | Not available | Not statistically significant, p > 0.05 |
|
Immunizations up to date, percentage | FavorableUnfavorable or ambiguousNo Effect |
2 years postnatal | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 671 children | % (adjusted) = 70.00 | Adjusted mean % = 68.00 | OR = 1.10 | HomVEE calculated = 0.06 | Not statistically significant, p > 0.05 |
footnote6The odds ratio compares the nurse-visited group to the comparison. |
Indicated preterm delivery (percentage) | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full, (Memphis) | 1082 children | % (adjusted) = 3.00 | Adjusted mean % = 3.00 | OR = 1.00 | HomVEE calculated = 0.00 | Not statistically significant, p > 0.05 |
footnote2Statistical significance reported on authors’ calculations of the odds ratio. footnote6The odds ratio compares the nurse-visited group to the comparison. |
Intrauterine growth restriction (percentage) | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full, (Memphis) | 1082 children | % (adjusted) = 9.00 | Adjusted mean % = 9.00 | OR = 1.00 | HomVEE calculated = 0.00 | Not statistically significant, p > 0.05 |
footnote2Statistical significance reported on authors’ calculations of the odds ratio. footnote6The odds ratio compares the nurse-visited group to the comparison. |
Low birth weight (percentage < 2500 g) | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full, (Memphis) | 1082 children | % (adjusted) = 15.00 | Adjusted mean % = 14.00 | OR = 1.10 | HomVEE calculated = 0.05 | Not statistically significant, p > 0.05 |
footnote2Statistical significance reported on authors’ calculations of the odds ratio. footnote6The odds ratio compares the nurse-visited group to the comparison. |
Number of well-child visits | FavorableUnfavorable or ambiguousNo Effect |
2 years postnatal | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 671 children | Adjusted mean = 4.60 | Adjusted mean = 4.80 | Mean difference = -0.20 | Not available | Not statistically significant, p > 0.05 |
|
Preterm (less than 37 weeks, percentage) | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full, (Memphis) | 1082 children | % (adjusted) = 11.00 | Adjusted mean % = 13.00 | OR = 0.80 | HomVEE calculated = -0.12 | Not statistically significant, p > 0.05 |
footnote2Statistical significance reported on authors’ calculations of the odds ratio. footnote6The odds ratio compares the nurse-visited group to the comparison. |
Spontaneous preterm delivery, percentage | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full, (Memphis) | 1082 children | % (adjusted) = 8.00 | Adjusted mean % = 9.00 | OR = 0.80 | HomVEE calculated = -0.08 | Not statistically significant, p > 0.05 |
footnote2Statistical significance reported on authors’ calculations of the odds ratio. footnote6The odds ratio compares the nurse-visited group to the comparison. |
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
---|---|---|---|---|---|---|---|---|---|---|
Number of subsequent low birth weight newborns (< 2500 g) | FavorableUnfavorable or ambiguousNo Effect |
3-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 646 mothers | Mean = 0.12 | Mean = 0.15 | Mean difference = -0.03 | Not available | Not statistically significant, p ≥ 0.05 |
footnote1Statistical significance reported on authors’ calculations of the log-incidence difference. |
Number of subsequent neonatal intensive care unit or special care admissions | FavorableUnfavorable or ambiguousNo Effect |
3-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 646 mothers | Mean = 0.14 | Mean = 0.20 | Mean difference = -0.06 | Not available | Not statistically significant, p ≥ 0.05 |
footnote1Statistical significance reported on authors’ calculations of the log-incidence difference. footnote3Authors report the difference in this outcome to be statistically significant, p < 0.10, which is greater than the acceptable alpha for this review (α = 0.05). |
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance |
---|---|---|---|---|---|---|---|---|---|
Night awake (mother-reported number of episodes last 2 weeks | FavorableUnfavorable or ambiguousNo Effect |
6 months | Nurse visited during pregnancy + infancy and comparison (Elmira) | 163 children | Adjusted mean = 2.69 | Adjusted mean = 2.83 | Mean difference = -0.14 | Not available | Not statistically significant, p > 0.05 |
Night awake (mother-reported number of episodes last 2 weeks | FavorableUnfavorable or ambiguousNo Effect |
6 months | Nurse visited during pregnancy and comparison (Elmira) | 164 children | Adjusted mean = 3.25 | Adjusted mean = 2.83 | Mean difference = 0.42 | Not available | Statistical significance not reported |
Number of emergency room visits (first year of life) | FavorableUnfavorable or ambiguousNo Effect |
1-year follow-up | Nurse visited during pregnancy and comparison (Elmira) | 205 children | Adjusted mean = 1.12 | Adjusted mean = 1.02 | Mean difference = 0.10 | Not available | Statistical significance not reported |
Number of emergency room visits (first year of life) | FavorableUnfavorable or ambiguousNo Effect |
1-year follow-up | Nurse visited during pregnancy + infancy and comparison (Elmira) | 223 children | Adjusted mean = 0.74 | Adjusted mean = 1.02 | Mean difference = -0.28 | Not available | Statistically significant, p < 0.05 |
Number of emergency room visits (second year of life) | FavorableUnfavorable or ambiguousNo Effect |
2-year follow-up | Nurse visited during pregnancy and comparison (Elmira) | 185 children | Adjusted mean = 1.04 | Adjusted mean = 1.09 | Mean difference = -0.05 | Not available | Statistical significance not reported |
Number of emergency room visits (second year of life) | FavorableUnfavorable or ambiguousNo Effect |
2-year follow-up | Nurse visited during pregnancy + infancy and comparison (Elmira) | 196 children | Adjusted mean = 0.74 | Adjusted mean = 1.09 | Mean difference = -0.35 | Not available | Statistically significant, p < 0.01 |
Resist eating (mother-reported number of episodes last 2 weeks) | FavorableUnfavorable or ambiguousNo Effect |
6 months | Nurse visited during pregnancy and comparison (Elmira) | 164 children | Adjusted mean = 2.01 | Adjusted mean = 1.72 | Mean difference = 0.29 | Not available | Statistical significance not reported |
Resist eating (mother-reported number of episodes last 2 weeks) | FavorableUnfavorable or ambiguousNo Effect |
6 months | Nurse visited during pregnancy + infancy and comparison (Elmira) | 163 children | Adjusted mean = 2.29 | Adjusted mean = 1.72 | Mean difference = 0.57 | Not available | Statistically significant, p < 0.01 |
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance |
---|---|---|---|---|---|---|---|---|---|
Child birth weight (grams) | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full (Elmira) | 308 children | Adjusted mean = 3285.00 | Adjusted mean = 3262.00 | Mean difference = 23.00 | Not available | Not statistically significant, p > 0.05 |
Length of gestation | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full (Elmira) | 308 children | Adjusted mean = 39.57 | Adjusted mean = 39.71 | Mean difference = -0.14 | Not available | Not statistically significant, p > 0.05 |
Percentage low birth rate, (≤ 2,500 grams) | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full (Elmira) | 308 children | % (adjusted) = 5.78 | Adjusted mean % = 2.61 | Mean difference = 3.17 | HomVEE calculated = 0.50 | Not statistically significant, p > 0.05 |
Percentage preterm delivery (< 37 weeks) | FavorableUnfavorable or ambiguousNo Effect |
Birth | Full (Elmira) | 308 children | % (adjusted) = 6.90 | Adjusted mean % = 7.27 | Mean difference = -0.37 | HomVEE calculated = -0.03 | Not statistically significant, p > 0.05 |
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
---|---|---|---|---|---|---|---|---|---|---|
Number of days hospitalized (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy and comparison (Elmira) | 209 children | Adjusted mean = 0.43 | Adjusted mean = 0.31 | Mean difference = 0.12 | Not available | Statistical significance not reported | |
Number of days hospitalized (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy + infancy and comparison (Elmira) | 221 children | Adjusted mean = 0.49 | Adjusted mean = 0.31 | Mean difference = 0.18 | Not available | Statistically significant, p ≤ 0.05 |
footnote1Statistical significance reported on authors’ calculations of the log-incidence difference. |
Number of emergency department visits (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy + infancy and comparison (Elmira) | 221 children | Adjusted mean = 1.00 | Adjusted mean = 1.53 | Mean difference = -0.53 | Not available | Statistically significant, p ≤ .01 |
footnote1Statistical significance reported on authors’ calculations of the log-incidence difference. |
Number of emergency department visits (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy and comparison (Elmira) | 209 children | Adjusted mean = 1.24 | Adjusted mean = 1.53 | Mean difference = -0.29 | Not available | Statistical significance not reported | |
Number of hospital admissions (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy and comparison (Elmira) | 209 children | Adjusted mean = 0.11 | Adjusted mean = 0.11 | Mean difference = 0.00 | Not available | Statistical significance not reported | |
Number of hospital admissions (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy + infancy and comparison (Elmira) | 221 children | Adjusted mean = 0.14 | Adjusted mean = 0.11 | Mean difference = 0.03 | Not available | Not statistically significant, p > 0.05 |
footnote1Statistical significance reported on authors’ calculations of the log-incidence difference. |
Number of scheduled health supervision visits (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy and comparison (Elmira) | 209 children | Adjusted mean = 1.27 | Adjusted mean = 1.56 | Mean difference = -0.29 | Not available | Statistical significance not reported | |
Number of scheduled health supervision visits (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy + infancy and comparison (Elmira) | 221 children | Adjusted mean = 1.26 | Adjusted mean = 1.56 | Mean difference = -0.30 | Not available | Not statistically significant, p > 0.05 |
|
Number of scheduled health supervision visits with problems (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy + infancy and comparison (Elmira) | 221 children | Adjusted mean = 6.24 | Adjusted mean = 6.72 | Mean difference = -0.48 | Not available | Not statistically significant, p > 0.05 |
|
Number of scheduled health supervision visits with problems (25 to 50 months) | FavorableUnfavorable or ambiguousNo Effect |
50 months | Nurse visited during pregnancy and comparison (Elmira) | 209 children | Adjusted mean = 5.18 | Adjusted mean = 6.72 | Mean difference = -1.54 | Not available | Statistical significance not reported |
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
---|---|---|---|---|---|---|---|---|---|---|
Subsequent NICU/special care admission (rate per subsequent birth) | FavorableUnfavorable or ambiguousNo Effect |
6-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 641 mothers | % (adjusted) = 18.00 | Adjusted mean % = 23.00 | OR = -0.72 | HomVEE calculated = -0.20 | Not statistically significant, p = 0.14 |
footnote2Statistical significance reported on authors’ calculations of the odds ratio. |
Subsequent low birth weight newborn (rate per subsequent birth) | FavorableUnfavorable or ambiguousNo Effect |
6-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 641 mothers | % (adjusted) = 11.00 | Adjusted mean % = 16.00 | OR = -0.69 | HomVEE calculated = -0.22 | Not statistically significant, p = 0.16 |
footnote2Statistical significance reported on authors’ calculations of the odds ratio. |
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
---|---|---|---|---|---|---|---|---|---|---|
Number of infant and childhood deaths among firstborn children (birth–9 years) | FavorableUnfavorable or ambiguousNo Effect |
9-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 627 mothers | per 1,000 = 4.50 per 1,000 | per 1,000 = 20.08 per 1,000 | OR = 0.22 | Not available | Not statistically significant, p = 0.80 |
footnote2Statistical significance reported on authors’ calculations of the odds ratio. |
Number of subsequent low birth weight newborns (0–9 years postpartum) | FavorableUnfavorable or ambiguousNo Effect |
9-year follow-up | Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis) | 627 mothers | Adjusted mean = 0.18 | Adjusted mean = 0.27 | Mean difference = -0.09 | Not available | Not statistically significant, p = 0.07 |
footnote4Statistical significance reported on authors’ calculation of incidence ratio. |
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance |
---|---|---|---|---|---|---|---|---|---|
Subsequent low birth weight newborns | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Nurse home visitor and comparison (Denver) | 424 mothers | = 0.06 | = 0.08 | OR = 0.75 | HomVEE calculated = -0.17 | Not statistically significant, p = 0.45 |
Subsequent special care admissions | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Nurse home visitor and comparison (Denver) | 424 mothers | = 0.06 | = 0.08 | OR = 0.66 | HomVEE calculated = -0.26 | Not statistically significant, p = 0.27 |
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
---|---|---|---|---|---|---|---|---|---|---|
Low birthweight of the second child |
FavorableUnfavorable or ambiguousNo Effect |
18 years |
Nurse Family Partnership vs. comparison, Memphis New Mother's Study 1990-1991, mothers with second child |
512 children | Not reported | Not reported | Odds ratio = 0.51 | Study reported = -0.41 | Statistically significant, p <0.05 |
Negative effect is favorableNegative effect is favorable to the intervention. Effect size based on study ORHomVEE calculated the effect size based on the study-reported odds ratio. |
Preterm birth of the second child |
FavorableUnfavorable or ambiguousNo Effect |
18 years |
Nurse Family Partnership vs. comparison, Memphis New Mother's Study 1990-1991, mothers with second child |
470 children | Not reported | Not reported | Odds ratio = 1.07 | Study reported = 0.04 | Not statistically significant, p ≥ 0.05 |
Negative effect is favorableNegative effect is favorable to the intervention. Effect size based on study ORHomVEE calculated the effect size based on the study-reported odds ratio. |
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance |
---|---|---|---|---|---|---|---|---|---|
Birth weight (grams) | FavorableUnfavorable or ambiguousNo Effect |
Birth | NFP-trained nurse visitors and comparison nurse visitors | 156 children | Mean = 3.00 | Mean = 3.00 | Mean difference = 164.26 | HomVEE calculated = 0.29 | Not reported |
Gestational age (months) | FavorableUnfavorable or ambiguousNo Effect |
Birth | NFP-trained nurse visitors and comparison nurse visitors | 154 children | Mean = 38.88 | Mean = 38.92 | Mean difference = -0.04 | HomVEE calculated = -0.02 | Not reported |
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance | Notes |
---|---|---|---|---|---|---|---|---|---|---|
20 year child mortality rate - all causes (Nurse home visits during pregnancy and infancy vs. developmental screening comparison) | FavorableUnfavorable or ambiguousNo Effect |
20 years | Nurse home visits during pregnancy and infancy vs. developmental screening comparison (Memphis) | 708 mother/child dyads | Unadjusted mean = 0.01 | Unadjusted mean = 0.03 | Mean difference = -0.02 | HomVEE calculated = -0.68 | Not statistically significant, p = 0.11 | footnote162Negative value is favorable to the intervention. |
20 year child mortality rate - preventable cause (Nurse home visits during pregnancy and infancy vs. developmental screening comparison) | FavorableUnfavorable or ambiguousNo Effect |
20 years | Nurse home visits during pregnancy and infancy vs. developmental screening comparison (Memphis) | 708 mother/child dyads | Unadjusted mean = 0.00 | Unadjusted mean = 0.02 | Mean difference = -0.02 | Not available | Statistically significant, p = 0.04 | footnote162Negative value is favorable to the intervention. |
Outcome measure | Effect | Follow-up timing | Sample | Sample size | Intervention group | Comparison group | Group difference | Effect size | Statistical significance |
---|---|---|---|---|---|---|---|---|---|
Subsequent low birth weight newborns | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Paraprofessional. home visitor and comparison (Denver) | 431 mothers | = 0.03 | = 0.08 | OR = 0.34 | HomVEE calculated = -0.64 | Statistically significant, p = 0.03 |
Subsequent special care admissions | FavorableUnfavorable or ambiguousNo Effect |
4-year follow-up | Paraprofessional home visitor and comparison (Denver) | 431 mothers | = 0.05 | = 0.08 | OR = 0.54 | HomVEE calculated = -0.38 | Not statistically significant, p = 0.13 |